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Leaking Troponin Comprehensive Content Access #949

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What is a troponin test High troponin levels may be a sign of a heart attack A troponin test looks for the protein troponin (there are two forms related to your heart, troponin i and troponin t) in your blood

Normally, troponin stays inside your heart muscle's cells, but damage to those cells — like the kind of damage from a heart attack — causes troponin to leak into your blood A troponin test measures the level of troponin in your blood Higher levels of troponin in your blood also mean more.

Troponin can be temporally elevated in some situations, a finding that is related to increased membrane permeability

53 the myocardial depressing factors released in sepsis and other inflammatory conditions cause troponin to be fragmented into low molecular weight particles in situ. (see diagnosis of acute myocardial infarction, section on 'definitions'.) however, troponin is not specific for acute thrombotic occlusion of a coronary artery, the most common precursor to acute myocardial infarction. Cardiac troponin (ctn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (acs) The term troponin leak is often used informally to describe elevated troponin levels when the cause is not a classic heart attack

The more precise clinical term for this finding is myocardial injury, which is defined as an elevated cardiac troponin value above the 99th percentile of the upper reference limit. Differential diagnosis unstable angina myocardial injury/ troponin leak tachyarrhythmia, severe hypertension, marathon running, stimulant use, chf exacerbation, hypotension, lack of clearance from renal failure, other Troponin levels are measured with a blood test, and high levels may be a sign of heart damage.

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